24 Hour Urine Cortisol Calculator

Introduction: The 24 Hour Urine Cortisol Calculator provides a convenient way to determine the total excretion of cortisol in a 24-hour urine collection. This calculation is essential in endocrinology and helps evaluate cortisol levels, aiding in the diagnosis and management of various medical conditions.

Formula: The formula utilized by the calculator is straightforward: Total Cortisol Excretion (µg) = Total Urine Volume (ml) × Cortisol Concentration (µg/ml).

How to Use:

  1. Enter the total volume of urine collected in milliliters (ml).
  2. Enter the concentration of cortisol in the urine in micrograms per milliliter (µg/ml).
  3. Click the “Calculate” button to obtain the total cortisol excretion.
  4. The result will be displayed below the button.

Example: If you input a total urine volume of 1500 ml with a cortisol concentration of 0.1 µg/ml, the calculator will display “Total Cortisol Excretion: 150 µg.”


  1. Q: Why measure cortisol in a 24-hour urine collection? A: 24-hour urine cortisol measurement helps assess cortisol production over an entire day, aiding in the diagnosis of conditions like Cushing’s syndrome.
  2. Q: What is the normal range for 24-hour urine cortisol excretion? A: Normal values vary, but typically fall within the range of 10 to 100 micrograms per 24 hours.
  3. Q: Can this calculator be used for random urine samples? A: No, it is specifically designed for 24-hour urine collections.
  4. Q: How does cortisol excretion vary throughout the day? A: Cortisol excretion is typically highest in the morning and lowest in the evening.
  5. Q: Can I input fractional values for urine volume and cortisol concentration? A: Yes, the calculator supports fractional values for more precise calculations.

Conclusion: The 24 Hour Urine Cortisol Calculator is a valuable tool for healthcare professionals involved in endocrinology and patients undergoing cortisol level assessments. It provides a quick and accurate estimate of the total cortisol excretion based on a 24-hour urine collection, aiding in the diagnosis and monitoring of adrenal function.

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